How much does compounded semaglutide cost at Ondra Health?

Compounded semaglutide at Ondra Health is $149 per month on the monthly plan; $279 every 2 months through Optio RX (about $140/month); $339 every 3 months (about $113/month); $649 for 6 months (about $108/month); or $1,149 for 12 months (about $96/month, the lowest available rate). The price is the same across all dose levels. You are only charged if a licensed provider prescribes the medication.

Is compounded semaglutide available in all 50 states?

Yes. Ondra Health has licensed provider coverage in all 50 U.S. states and Puerto Rico. Pharmacy availability may vary by state and formulation. Optio RX serves all 50 states but does not ship to Puerto Rico.

How long does it take to get compounded semaglutide from Ondra Health?

Provider review typically takes under 24 hours. After a prescription is approved, medication ships from a licensed compounding pharmacy in 2 to 5 business days with free shipping.

What is the semaglutide dosing schedule at Ondra Health?

The typical starting dose is 0.25mg per week for the first 4 weeks, increasing gradually — typically every 4 weeks — through 0.5mg, 1mg, 1.5mg, and up to 2.5mg per week. Doses are titrated by your licensed provider based on your individual response and tolerance.

What pharmacies does Ondra Health use for compounded semaglutide?

Ondra Health partners with state-licensed 503A compounding pharmacies for semaglutide: Hallandale Pharmacy (no additives), Boudreaux's New Drug Store (with glycine), Vials RX (with B12 or with glycine), Southend Pharmacy (with B6), Drug Crafters Pharmacy (with B6 or with glycine), and Optio RX (with B3 (Niacinamide); not available in Puerto Rico). Pharmacy assignment is based on your state and formulation choice.

Is compounded semaglutide FDA-approved?

No. Compounded semaglutide is not FDA-approved. It is prepared by state-licensed 503A compounding pharmacies and prescribed by a licensed healthcare provider based on your individual health profile.

What are the common side effects of semaglutide?

Common side effects include nausea (especially when starting), reduced appetite, mild fatigue, diarrhea or constipation, headache, and injection site reactions. Less common effects include vomiting, heartburn, and temporary hair thinning. Your provider reviews your personal risk profile before prescribing.

How does semaglutide work for weight loss?

Semaglutide is a GLP-1 receptor agonist that works by suppressing appetite through brain receptors, delaying gastric emptying so you feel full longer, and regulating insulin and glucagon for blood sugar control. In clinical trials of the branded FDA-approved product (Wegovy), participants lost an average of approximately 15% of body weight; compounded semaglutide has not been studied in these trials and individual results vary.

GLP-1 Medical Weight Management

Compounded
Semaglutide

Name: Compounded Semaglutide
Brand: Ondra Health

A weekly injectable GLP-1 medication, personalized by a licensed provider. Real clinical care — shipped directly to you.

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HIPAA Compliant

Compounded in the U.S.A.

Free shipping

Semaglutide

$149/mo

Billed monthly · Same price on all doses

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Selection:1 monthHallandale

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Only charged if prescribed by your provider

*Compounded medications are not FDA-approved. Prepared by state-licensed pharmacies. Prescribed at provider discretion.

Semaglutide pricing

Plan	Per month*	Amount billed
Monthly	$149	$149 monthly
2 months (Optio RX)	~$140	$279 every 2 months
3 months	$113	$339 upfront
6 months	~$108	$649 upfront
12 months	~$96	$1,149 upfront

*Monthly equivalents rounded. Multi-month totals are paid upfront after prescribing. Same price at every dose. Includes consultation, medication, supplies and shipping; no membership fee.

2-month plans use Optio RX. 6/12-month plans use Hallandale or Vials RX. Other terms depend on pharmacy. Availability varies by state, prescription and inventory. Compounded drugs are not FDA-approved.

~15%

Avg weight loss in clinical studies†

<24h

Typical provider review time

2 to 5 days

Delivery after approval

50 states

Licensed coverage, plus Puerto Rico

†Average weight loss figure reflects findings from the STEP-1 trial of branded semaglutide (Wilding et al., NEJM 2021). That result reflects an FDA-approved finished product, not compounded semaglutide, and individual results vary.

The Medication

What is Semaglutide?

Semaglutide is a GLP-1 receptor agonist — a class of medication that works by mimicking a naturally occurring hormone to support sustainable weight loss.

Once-weekly injection

Administered subcutaneously once a week using a small insulin-type syringe.

Gradual dose titration

Doses start low and increase over time, guided by your provider based on your response.

Compounded formulation

Prepared by state-licensed 503A pharmacies with optional supportive additives. Not FDA-approved.

How it works — mechanism of action

Appetite suppression

Activates GLP-1 receptors in the brain to reduce hunger signals and increase feelings of fullness.

Gastric emptying delay

Slows how quickly food leaves your stomach, helping you feel satisfied longer after meals.

Insulin regulation

Stimulates insulin release in response to food and lowers glucagon, supporting blood sugar control.

The Process

How it works

Simple, transparent, and designed around your comfort.

Complete a short intake

A 3-minute online health intake — no appointments, no waiting rooms.

Provider review

A licensed provider personally reviews your profile within 24 hours.

Prescription issued

If approved, your provider issues a personalized prescription with dosing instructions.

Delivered to your door

Ships from a licensed pharmacy in 2 to 5 business days. Free shipping, always.

Dosing

A gradual progression

Doses start low and increase over time as your body adjusts. Your provider determines your personal schedule.

0.25mg

Month 1

Starting dose

0.5mg

Month 2

1mg

Month 3

1.5mg

Month 4

2.5mg

Month 5+

Max dose

*Dose schedule is illustrative. Your provider determines the appropriate titration. Same price across all dose levels.

Dose Calculator

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Questions about how much to inject?

Formulation

What's in your formulation?

Depending on your pharmacy, your compounded semaglutide may include a supportive additive. Where a pharmacy offers more than one option, each formulation contains a single additive.

B3 (Niacinamide)

Optio RX

Niacinamide is a form of vitamin B3.

Vitamin B12

Vials RX

Supports energy metabolism and nerve function. Included as a co-factor for patients who experience early fatigue on GLP-1 therapy.

Glycine

Boudreaux's New Drug Store · Vials RX · Drug Crafters Pharmacy

An amino acid stabilizer that helps preserve peptide integrity. Also plays a role in collagen synthesis and sleep quality.

Vitamin B6

Southend Pharmacy · Drug Crafters Pharmacy

Involved in amino acid metabolism and neurotransmitter production. Sometimes included to support tolerability during early titration.

No Additives

Hallandale Pharmacy

Pure semaglutide with no supportive additives — for patients who prefer or clinically require a simpler formulation.

What to Expect

Side effects overview

Your provider will review your personal risk profile before prescribing. Individual experiences vary.

Common (usually mild & temporary)

Nausea (especially when starting)

Reduced appetite

Mild fatigue

Diarrhea or constipation

Headache

Injection site reactions

Less common — discuss with your provider

Vomiting

Heartburn or reflux

Abdominal discomfort

Heart rate changes

Hair thinning (temporary)

Mood changes (rare)

Have questions?

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*Only charged if prescribed. Compounded medications are not FDA-approved.

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